Fibroblasts as efficient antigen-presenting cells in lymphoid organs.
Only so-called "professional" antigen-presenting cells (APCs) of hematopoietic origin are believed capable of inducing T lymphocyte responses. However, fibroblasts transfected with viral proteins directly induced antiviral cytotoxic T lymphocyte responses in vivo, without involvement of ho...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1995
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