Successful treatment of childhood-onset Cushing's disease is associated with persistent reduction in growth hormone secretion.

OBJECTIVE: Although Cushing's disease (CD) rarely occurs in childhood, affected children commonly fail to achieve predicted adult height. Hypercortisolaemia results in reduced GH secretion and GH-deficiency may persist or demonstrate delayed recovery after successful treatment of CD in adults....

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Bibliographic Details
Main Authors: Carroll, P, Monson, J, Grossman, AB, Besser, G, Plowman, P, Afshar, F, Savage, M
Format: Journal article
Language:English
Published: 2004