TDP-43 based biomarker development in amyotrophic lateral sclerosis

TDP-43 based biomarker development in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease which is clinically and aetiologically heterogenous. However, TDP-43 neuropathology is a unifying hallmark found in 97% of ALS cases. Understanding the common pathological pathways downstream of TDP-43 dysregulation is essentia...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Feneberg, E
अन्य लेखक:	Turner, M
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2019
विषय:	Proteomics Nervous system > Degeneration Molecular neurobiology Amyotrophic lateral sclerosis

समान संसाधन

Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis
द्वारा: Rachel H. Tan, और अन्य
प्रकाशित: (2023-11-01)

Advancements in TDP-43 research: Towards biomarkers and therapeutic targets for amyotrophic lateral sclerosis
द्वारा: Yuhan Wu, और अन्य
प्रकाशित: (2025-03-01)

The role of TDP-43 protein in amyotrophic lateral sclerosis
द्वारा: Piotr Włodarczyk, और अन्य
प्रकाशित: (2022-12-01)

Kinesitherapy in amyotrophic lateral sclerosis
द्वारा: Joanna Iłżecka
प्रकाशित: (2017-12-01)

Kinesitherapy in amyotrophic lateral sclerosis
द्वारा: Joanna Iłżecka
प्रकाशित: (2017-12-01)

Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions
द्वारा: Fumiaki Mori, और अन्य
प्रकाशित: (2019-10-01)

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
द्वारा: Archana Prasad, और अन्य
प्रकाशित: (2019-02-01)

TDP-43 and Phosphorylated TDP-43 Levels in Paired Plasma and CSF Samples in Amyotrophic Lateral Sclerosis
द्वारा: Yuting Ren, और अन्य
प्रकाशित: (2021-06-01)

TDP-43 as a potential biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis
द्वारा: Vivek Majumder, और अन्य
प्रकाशित: (2018-06-01)

TDP-43 pathology is sufficient to drive axon initial segment plasticity and hyperexcitability of spinal motoneurones in vivo in the TDP43-ΔNLS model of Amyotrophic Lateral Sclerosis
द्वारा: Svetlana Djukic, और अन्य
प्रकाशित: (2025-02-01)

TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis
द्वारा: Sarah Lépine, और अन्य
प्रकाशित: (2022-12-01)

Editorial: New Insights Into the Molecular Mechanism of Amyotrophic Lateral Sclerosis Pathogenesis
द्वारा: Cheng Li, और अन्य
प्रकाशित: (2022-06-01)

The effect of pH alterations on TDP-43 in a cellular model of amyotrophic lateral sclerosis
द्वारा: Yara Al Ojaimi, और अन्य
प्रकाशित: (2024-07-01)

TDP-43 Proteinopathy Specific Biomarker Development
द्वारा: Isabell Cordts, और अन्य
प्रकाशित: (2023-02-01)

Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis
द्वारा: D. Y. Mengistu, और अन्य
प्रकाशित: (2025-02-01)

Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis
द्वारा: Minggang Fang, और अन्य
प्रकाशित: (2023-10-01)

A panel of TDP-43-regulated splicing events verifies loss of TDP-43 function in amyotrophic lateral sclerosis brain tissue
द्वारा: Maize C. Cao, और अन्य
प्रकाशित: (2023-09-01)

Current insights in the molecular genetic pathogenesis of amyotrophic lateral sclerosis
द्वारा: Wan Zhou, और अन्य
प्रकाशित: (2023-08-01)

Dissecting the contribution of dipeptide repeats to the toxicity in C9orf72 iPSC-derived neurons from ALS/FTD patients
द्वारा: Barbagallo, P
प्रकाशित: (2021)

Analysis of Heart Rate Variability in Individuals Affected by Amyotrophic Lateral Sclerosis
द्वारा: Rosa Maset-Roig, और अन्य
प्रकाशित: (2024-04-01)

Neuronal TDP-43 aggregation drives changes in microglial morphology prior to immunophenotype in amyotrophic lateral sclerosis
द्वारा: Molly E. V. Swanson, और अन्य
प्रकाशित: (2025-02-01)

Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis
द्वारा: Matthew D. Cykowski, और अन्य
प्रकाशित: (2018-04-01)

Proteomics Analysis of Lymphoblastoid Cell Lines from Patients with Amyotrophic Lateral Sclerosis
द्वारा: Danielle Whitham, और अन्य
प्रकाशित: (2023-02-01)

A Computational Approach to Investigate TDP-43 RNA-Recognition Motif 2 C-Terminal Fragments Aggregation in Amyotrophic Lateral Sclerosis
द्वारा: Greta Grassmann, और अन्य
प्रकाशित: (2021-12-01)

Altered TDP-43 Structure and Function: Key Insights into Aberrant RNA, Mitochondrial, and Cellular and Systemic Metabolism in Amyotrophic Lateral Sclerosis
द्वारा: Leanne Jiang, और अन्य
प्रकाशित: (2022-07-01)

Depression in amyotrophic lateral sclerosis
द्वारा: Joanna Iłżecka
प्रकाशित: (2021-10-01)

Amyotrophic lateral sclerosis : advances and perspectives of neuronanomedicine /
द्वारा: Machtoub, Lina, author, और अन्य
प्रकाशित: (2016)

TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
द्वारा: Rachel Atkinson, और अन्य
प्रकाशित: (2021-02-01)

Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain
द्वारा: Molly E. V. Swanson, और अन्य
प्रकाशित: (2023-04-01)

Amyotrophic Lateral Sclerosis: A Diet Review
द्वारा: Salvatore D’Antona, और अन्य
प्रकाशित: (2021-12-01)

Pain in Amyotrophic Lateral Sclerosis Is Underrated
द्वारा: Soyoung Kwak, और अन्य
प्रकाशित: (2024-12-01)

Evaluation of Dysphagia in Amyotrophic Lateral Sclerosis
द्वारा: Xiao QIU, और अन्य
प्रकाशित: (2017-02-01)

An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis
द्वारा: Barbara Poletti, और अन्य
प्रकाशित: (2023-12-01)

Studies of Genetic and Proteomic Risk Factors of Amyotrophic Lateral Sclerosis Inspire Biomarker Development and Gene Therapy
द्वारा: Eva Bagyinszky, और अन्य
प्रकाशित: (2023-07-01)

Bulbar involvement and cognitive features in amyotrophic lateral sclerosis: a retrospective study on 347 patients
द्वारा: Edoardo Nicolò Aiello, और अन्य
प्रकाशित: (2023-07-01)

Metabolic rate and insulin-independent glucose uptake increase in a TDP-43Q331K mouse model of amyotrophic lateral sclerosis
द्वारा: Tanya S. McDonald, और अन्य
प्रकाशित: (2025-02-01)

Cerebrospinal Fluid Chitinases as Biomarkers for Amyotrophic Lateral Sclerosis
द्वारा: Júlia Costa, और अन्य
प्रकाशित: (2021-07-01)

Cerebral degeneration in amyotrophic lateral sclerosis revealed by 3-dimensional texture analysis
द्वारा: Rouzbeh eMaani, और अन्य
प्रकाशित: (2016-03-01)

New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022
द्वारा: JingSi Jiang, और अन्य
प्रकाशित: (2022-11-01)

Progress in clinical diagnosis of amyotrophic lateral sclerosis
द्वारा: Qiong YANG, और अन्य
प्रकाशित: (2012-06-01)