TDP-43 based biomarker development in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease which is clinically and aetiologically heterogenous. However, TDP-43 neuropathology is a unifying hallmark found in 97% of ALS cases. Understanding the common pathological pathways downstream of TDP-43 dysregulation is essentia...
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| 格式: | Thesis |
| 语言: | English |
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2019
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