Systems-level feedback in cell-cycle control.

Alternation of chromosome replication and segregation is essential for successful completion of the cell cycle and it requires an oscillation of Cdk1 (cyclin-dependent kinase 1)-CycB (cyclin B) activity. In the present review, we illustrate the essential features of checkpoint controlled and uncontr...

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Détails bibliographiques
Auteurs principaux: Novák, B, Vinod, P, Freire, P, Kapuy, O
Format: Journal article
Langue:English
Publié: 2010