A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding

As well as being expressed as a full-length transcript, the group II metabotropic glutamate receptor 3 (GRM3, mGlu3) gene is expressed as an mRNA isoform which lacks exon 4 (GRM3Δ4) and which is predicted to encode a protein with a novel C terminus (called mGlu3 ∆4). This variant may contribute to t...

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Bibliographic Details
Main Authors: Garcia-Bea, A, Bermudez, I, Harrison, P, Lane, T
Format: Journal article
Published: SAGE Publications 2017