Dimensions and interactions of large T-cell surface proteins

The first step of the adaptive immune response involves the interaction of T cells that express T-cell receptors (TCRs) with peptide-loaded major histocompatibility complexes expressed by antigen-presenting cells (APCs). Exactly how this leads to activation of the TCR and to downstream signaling is...

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Bibliographic Details
Main Authors: Junghans, V, Santos, AM, Lui, Y, Davis, SJ, Jönsson, P
Format: Journal article
Language:English
Published: Frontiers Media 2018