NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone

Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors. Here, we show that nerve growth factor (NGF) signaling through neurotrophic tyrosine kinase receptor type 1 (TrkA)...

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Váldodahkkit: Tomlinson, R, Li, Z, Zhang, Q, Goh, B, Thorek, D, Rajbhandari, L, Brushart, T, Minichiello, L, Zhou, F, Venkatesan, A, Clemens, T
Materiálatiipa: Journal article
Almmustuhtton: Cell Press 2016