NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone

NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone

Mostrar outras versões (1)

Developing tissues dictate the amount and type of innervation they require by secreting neurotrophins, which promote neuronal survival by activating distinct tyrosine kinase receptors. Here, we show that nerve growth factor (NGF) signaling through neurotrophic tyrosine kinase receptor type 1 (TrkA)...

ver descrição completa

Detalhes bibliográficos
Principais autores:	Tomlinson, R, Li, Z, Zhang, Q, Goh, B, Thorek, D, Rajbhandari, L, Brushart, T, Minichiello, L, Zhou, F, Venkatesan, A, Clemens, T
Formato:	Journal article
Publicado em:	Cell Press 2016

Registros relacionados

NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of developing endochondral bone
por: Tomlinson, R, et al.
Publicado em: (2016)

NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone
por: Ryan E. Tomlinson, et al.
Publicado em: (2016-09-01)

NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice
por: Tomlinson, R, et al.
Publicado em: (2017)

NGF causes TrkA to specifically attract microtubules to lipid rafts.
por: Shona Pryor, et al.
Publicado em: (2012-01-01)

Postnatal changes in the expression of the trkA high-affinity NGF receptor in primary sensory neurons.
por: Bennett, D, et al.
Publicado em: (1996)

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA
por: Simon Desiderio, et al.
Publicado em: (2019-03-01)

Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling
por: Mengchen Ye, et al.
Publicado em: (2018-01-01)

Role of NGF/TrkA signaling milieu in depressogenic induction of rat brain
por: Ritabrata Banerjee, et al.
Publicado em: (2013-10-01)

Engineered Sensory Nerve Guides Self‐Adaptive Bone Healing via NGF‐TrkA Signaling Pathway
por: Zengjie Zhang, et al.
Publicado em: (2023-04-01)

NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
por: Lee, S, et al.
Publicado em: (2021)

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling
por: Hoi Leong Xavier Wong, et al.
Publicado em: (2019-04-01)

Loss of NGF-TrkA signaling from the CNS is not sufficient to induce cognitive impairments in young adult or intermediate-aged mice.
por: Müller, M, et al.
Publicado em: (2012)

NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
por: Seungyong Lee, et al.
Publicado em: (2021-08-01)

72. The Role of TrkA And P75NTR NGF Receptors in Corneal Wound Healing
por: Kiana Tajdaran, MD, MASc, et al.
Publicado em: (2022-06-01)

Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGF.
por: Fernando C Alsina, et al.
Publicado em: (2012-01-01)

Testicular expression of NGF, TrkA and p75 during seasonal spermatogenesis of the wild ground squirrel (Citellus dauricus Brandt)
por: H. Zhang, et al.
Publicado em: (2015-08-01)

hNGF Peptides Elicit the NGF-TrkA Signalling Pathway in Cholinergic Neurons and Retain Full Neurotrophic Activity in the DRG Assay
por: Viviana Triaca, et al.
Publicado em: (2020-02-01)

Effects of castration on the expression of the NGF and TrkA in the vas deferens and accessory male genital glands of the rat
por: N. Mirabella, et al.
Publicado em: (2009-12-01)

Effects of castration on the expression of the NGF and TrkA in the vas deferens and accessory male genital glands of the rat
por: C. Squillacioti, et al.
Publicado em: (2009-12-01)

QS8: The Roles of the TrkA and p75NTR NGF Receptors in Corneal Wound Healing
por: Kiana Tajdaran, et al.
Publicado em: (2021-07-01)

IMMUNOHISTOCHEMICAL EXPRESSION OF NGF/TrkA AND BDNF/TrkB IN TUMOR PARIENCHYMA AND PERIPROSTATIC ADIPOSE TISSUE, DEPENDING ON THE PATHOANATOMIC STAGE OF PROSTATE CANCER
por: Nikolay Evtimov
Publicado em: (2024-02-01)

Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats
por: Ashley M. Fortress, et al.
Publicado em: (2011-01-01)

Upregulation of NGF/TrkA-Related Proteins in Dorsal Root Ganglion of Paclitaxel-Induced Peripheral Neuropathy Animal Model
por: Kim Y, et al.
Publicado em: (2024-11-01)

NGF与TrkA受体在儿童膀胱过度活动症中的研究进展
por: 何萍, et al.
Publicado em: (2024-05-01)

Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease
por: Erika Kropf, et al.
Publicado em: (2021-08-01)

NGF Prevents Loss of TrkA/VEGFR2 Cells, and VEGF Isoform Dysregulation in the Retina of Adult Diabetic Rats
por: Elena Fico, et al.
Publicado em: (2022-10-01)

Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
por: Sarah Trouvilliez, et al.
Publicado em: (2022-03-01)

Hedgehog Signaling in Endochondral Ossification
por: Shinsuke Ohba
Publicado em: (2016-06-01)

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR
por: Erika Kropf, et al.
Publicado em: (2023-11-01)

Expression of NGF, Trka and p75 in human cartilage
por: A Gigante, et al.
Publicado em: (2009-06-01)

Correction: The Long Coiled-Coil Protein NECC2 Is Associated to Caveolae and MODULATES NGF/TrkA Signaling IN PC12 CELLS
Publicado em: (2013-01-01)

Correction: The Long Coiled-Coil Protein NECC2 Is Associated to Caveolae and MODULATES NGF/TrkA Signaling IN PC12 CELLS.
por: Alberto Díaz-Ruiz, et al.
Publicado em: (2013-01-01)

Secreted herpes simplex virus-2 glycoprotein G modifies NGF-TrkA signaling to attract free nerve endings to the site of infection.
por: Jorge Rubén Cabrera, et al.
Publicado em: (2015-01-01)

Whole-tissue 3D imaging reveals intra-adipose sympathetic plasticity regulated by NGF-TrkA signal in cold-induced beiging
por: Ying Cao, et al.
Publicado em: (2018-03-01)

Neuritogenic effect of sea cucumber glucocerebrosides on NGF-induced PC12 cells via activation of the TrkA/CREB/BDNF signalling pathway
por: Xiaoxu Wang, et al.
Publicado em: (2018-07-01)

Hypoxia inhibits hypertrophic differentiation and endochondral ossification in explanted tibiae.
por: Jeroen C H Leijten, et al.
Publicado em: (2012-01-01)

Endochondral ossification in vitro is influenced by mechanical bending.
por: Trepczik, B, et al.
Publicado em: (2007)

Histological Assessment of Endochondral Ossification and Bone Mineralization
por: Tomoka Hasegawa, et al.
Publicado em: (2023-02-01)

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells
por: Julien Cicero, et al.
Publicado em: (2023-12-01)

The Occurrence of Valvular Atrial Fibrillation: Involvement of NGF/TrKA Signaling Pathway
por: Qianli Wang, et al.
Publicado em: (2021-11-01)