Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation

Oxygen heterogeneity in solid tumors is recognized as a limiting factor for therapeutic efficacy. This heterogeneity arises from the abnormal vascular structure of the tumor, but the precise mechanisms linking abnormal structure and compromised oxygen transport are only partially understood. In this...

Full description

Bibliographic Details
Main Authors: Bernabeu, M, Kory, J, Grogan, J, Markelc, B, Beardo, A, D'Avezac, M, Enjalbert, R, Kaeppler, J, Daly, N, Hetherington, J, Kruger, T, Maini, P, Pitt-Francis, J, Muschel, R, Alarcon, T, Byrne, H
Format: Journal article
Language:English
Published: National Academy of Sciences 2020