Aggrecanases in cartilage matrix breakdown

Aggrecanases in cartilage matrix breakdown

In rheumatoid arthritis and osteoarthritis, the loss of extracellular matrix macromolecules, aggrecan and collagens exceeds new production, resulting in serious joint impairment. The primary cause of this loss is due to elevated proteolytic enzyme activities. Recent studies have suggested that the e...

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Chi tiết về thư mục
Tác giả chính:	Nagase, H
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2001

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