Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana.

Agroinfiltrated Nicotiana benthamiana is a flexible and scalable platform for recombinant protein (RP) production, but its great potential is hampered by plant proteases that degrade RPs. Here, we tested 29 candidate protease inhibitors (PIs) in agroinfiltrated N. benthamiana leaves for enhancing ac...

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Những tác giả chính: Grosse-Holz, F, Madeira, L, Zahid, MA, Songer, M, Kourelis, J, Fesenko, M, Ninck, S, Kaschani, F, Kaiser, M, van der Hoorn, RAL
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Wiley 2018