Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates.

Neonatal hypoxic ischaemic (HI) injury frequently causes neural impairment in surviving infants. Our knowledge of the underlying molecular mechanisms is still limited. Protein deimination is a post-translational modification caused by Ca(+2) -regulated peptidylarginine deiminases (PADs), a group of...

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Bibliographic Details
Main Authors: Lange, S, Rocha-Ferreira, E, Thei, L, Mawjee, P, Bennett, K, Thompson, P, Subramanian, V, Nicholas, A, Peebles, D, Hristova, M, Raivich, G
Format: Journal article
Language:English
Published: 2014