Intramolecular cyclopropanation of epichlorohydrin-derived unsaturated chlorohydrins
Concise stereoselective syntheses of bicyclo[3.1.0]hexan-2-ols and a bicyclo[4.1.0]heptan-2-ol are achieved via regioselective ring-opening of epichlorohydrin with allylic and homoallylic Grignard reagents, followed by lithium 2,2,6,6-tetramethylpiperidide-induced intramolecular cyclopropanation of...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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