Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance.

An efficacious vaccine strategy must be capable of inducing strong responses of an appropriate phenotype that are long lasting and sufficiently broad to prevent pathogen escape mechanisms. In the present study, we use anti-CD25 mAb to augment vaccine-induced immunity in mice. We demonstrate that cof...

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Bibliographic Details
Main Authors: Moore, A, Gallimore, A, Draper, S, Watkins, K, Gilbert, S, Hill, A
Format: Journal article
Language:English
Published: 2005