The molecular pathogenesis of FUS mutations in amyotrophic lateral sclerosis using in vivo and in vitro models
<p>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by degeneration of both upper and lower motor neurons. Most ALS occurs in a sporadic manner, though 5-10% is familial. Fused in sarcoma (FUS) is an RNA binding protein, and mutations in the FUS gene are respon...
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| Format: | Thesis |
| Language: | English |
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2015
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