Potential disease targets for drugs that disrupt protein-- protein interactions of Grb2 and Crk family adaptors.

This review summarises some of the knowledge we have about Crk and Grb2 family adaptor protein signalling in health and disease and outlines the current status and the challenges still remaining in the development of efficient and selective inhibitors of their protein - protein interactions. It also...

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Bibliographic Details
Main Authors: Feller, S, Lewitzky, M
Format: Journal article
Language:English
Published: 2006