Purification and characterization of endogenous peptides extracted from HLA-DR isolated from the spleen of a patient with rheumatoid arthritis.

We have purified HLA-DR from the spleen of a patient with rheumatoid arthritis. The patient had Felty's syndrome and was heterozygous for the DR4Dw4 antigen. We have isolated endogenous peptides from purified HLA-DR molecules. The peptides were purified by reverse phase HPLC and the major peaks...

Full description

Bibliographic Details
Main Authors: Gordon, R, Young, J, Rayner, S, Luke, R, Crowther, M, Wordsworth, P, Bell, J, Hassall, G, Evans, J, Hinchliffe, SA
Format: Journal article
Language:English
Published: 1995