An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

<p>NP<sub>105–113</sub>-B*07:02-specific CD8<sup>+</sup> T cell responses are considered among the most dominant in SARS-CoV-2-infected individuals. We found strong association of this response with mild disease. Analysis of NP<sub>105&ndash...

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Bibliographic Details
Main Authors:	Peng, Y, Felce, SL, Dong, D, Penkava, F, Mentzer, AJ, Yao, X, Liu, G, Yin, Z, Chen, J-L, Lu, Y, Wellington, D, Wing, PAC, Dominey-Foy, DCC, Jin, C, Wang, W, Hamid, MA, Fernandes, RA, Wang, B, Fries, A, Zhuang, X, Ashley, N, Rostron, T, Waugh, C, Sopp, P, Hublitz, P, Beveridge, R, Tan, TK, Dold, C, Kwok, AJ, Rich-Griffin, C, Dejnirattisa, W, Liu, C, Kurupati, P, Nassiri, I, Watson, RA, Tong, O, Taylor, CA, Kumar Sharma, P, Sun, B, Curion, F, Revale, S, Garner, LC, Jansen, K, Ferreira, RC, Attar, M, Fry, JW, Russell, RA, Stauss, HJ, James, W, Townsend, A, Ho, L-P, Klenerman , P, Mongkolsapaya , P, Screaton, GR, Dendrou, C, Sansom , SN, Bashford-Rogers, R, Chain , B, Smith , GL, McKeating, JA, Fairfax, BP, Bowness , P, McMichael, AJ, Ogg, G, Knight, JC, Dong, T
Other Authors:	COMBAT Consortium
Format:	Journal article
Language:	English
Published:	Springer Nature 2021