Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Manylion Llyfryddiaeth
Prif Awduron:	Boultwood, J, Perry, J, Pellagatti, A, Fernandez-Mercado, M, Fernandez-Santamaria, C, Calasanz, M, Larrayoz, M, Garcia-Delgado, M, Giagounidis, A, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2010

Eitemau Tebyg

Frequent Mutation of the Polycomb-Associated Gene ASXL1 in the Myelodysplastic Syndromes and in Acute Myeloid Leukaemia
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Frequent Mutation of the Polycomb-Associated Gene ASXL1 In Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
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Deregulated Gene Expression Pathways in Myelodysplastic Syndrome Hematopoietic Stem Cells
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Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
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Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome.
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Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
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Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells.
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Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
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Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
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Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes.
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Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes (British Journal of Haematology (2008) 142, (57-64))
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Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.
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Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q)
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Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.
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COMPREHENSIVE ANALYSIS OF MUTATION STATUS, GENE EXPRESSION PROFILES, BLOOD AND BONE MARROW COUNTS AND OUTCOME IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES
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Genome-wide analysis of copy number change and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density SNP arrays
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Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia
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Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia.
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Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.
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The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts
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Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.
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Lenalidomide selectively inhibits in vitro growth of the malignant clone in myelodysplastic syndrome (MDS) patients with 5q deletion.
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Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34+ progenitor cells
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Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34⁺ progenitor cells.
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Identification of aberrant splicing events in myelodysplastic syndrome patients with splicing factor gene mutations
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High-resolution genomic profiling of myelodysplasia (MDS) by microarray comparative genomic hybridization (CGH).
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Mutations in SETBP1 are recurrent in myelodysplastic syndromes and often coexist with cytogenetic markers associated with disease progression.
gan: Fernandez-Mercado, M, et al.
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Mutations in SETBP1 are recurrent in myelodysplastic syndromes and often coexist with cytogenetic markers associated with disease progression
gan: Fernandez-Mercado, M, et al.
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The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts.
gan: Jacqueline Boultwood, et al.
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Gene expression profiling in the myelodysplastic syndromes.
gan: Pellagatti, A, et al.
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Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.
gan: Pellagatti, A, et al.
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Genome-wide analysis of copy number changes and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density single nucleotide polymorphism arrays.
gan: Wang, L, et al.
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Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q).
gan: Pellagatti, A, et al.
Cyhoeddwyd: (2004)

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes
gan: Marta Fernandez-Mercado, et al.
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Haploinsufficiency of RPS14 and Deregulation of Ribosomal- and Translation-Related Genes in MDS Patients with Del(5q)
gan: Pellagati, A, et al.
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Del(5q) Myelodysplastic Stem Cells Exhibit Their Clonal Advantage Via Increased Adhesion to the Microenvironment
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