Genetic disorders associated with cancer predisposition and genomic instability.
Genomic instability in its broadest sense is a feature of virtually all neoplastic cells. In addition to the mutations and/or gene amplifications that appear to be a prerequisite for the acquisition of a neoplastic phenotype, human cancers exhibit other "markers" of genomic instability--in...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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