Genetic disorders associated with cancer predisposition and genomic instability.

Genomic instability in its broadest sense is a feature of virtually all neoplastic cells. In addition to the mutations and/or gene amplifications that appear to be a prerequisite for the acquisition of a neoplastic phenotype, human cancers exhibit other "markers" of genomic instability--in...

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Autori principali: Vessey, C, Norbury, C, Hickson, I
Natura: Journal article
Lingua:English
Pubblicazione: 1999