Dominant CD4-dependent RNA-dependent RNA polymerase-specific T-cell responses in children acutely infected with human enterovirus 71 and healthy adult controls.

Human enterovirus 71 (EV71) is one of the major causes of hand, foot and mouth disease (HFMD), which leads to significant mortality in infected children. A prophylactic vaccine is urgently needed. However, little is known about the protective T-cell immunity in individuals infected with the EV71 vir...

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Bibliographic Details
Main Authors: Dang, S, Gao, N, Li, Y, Li, M, Wang, X, Jia, X, Zhai, S, Zhang, X, Liu, J, Deng, H, Dong, T
Format: Journal article
Language:English
Published: Blackwell Publishing Ltd 2014