Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export.
The poly(A) tail of influenza virus mRNA is synthesized by reiterative copying of a U track near the 5' end of the virion RNA (vRNA) template by the viral RNA polymerase. We have engineered a novel influenza A/WSN/33 virus which contains a neuraminidase (NA) vRNA with its U track mutated into a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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