Incomplete response of inflammatory arthritis to TNF alpha blockade is associated with the Th17 pathway

Objectives: To establish if changes in Th1/Th17 cell populations previously reported in experimental arthritis occur in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor α (TNFα) agents, and whether the therapeutic response to anti-TNFα is compromised in patients and m...

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Bibliographic Details
Main Authors: Alzabin, S, Abraham, S, Taher, T, Palfreeman, A, Hull, D, McNamee, K, Jawad, A, Pathan, E, Kinderlerer, A, Taylor, P, Williams, R, Mageed, R
Format: Journal article
Language:English
Published: 2012