An osteo-inductive bone matrix extract stimulates the in vitro conversion of mesenchyme into chondrocytes.
Urea and guanidine extracts of demineralized beef and rabbit bone matrix were assayed both in vivo and in vitro. One month following intramuscular implantation into mouse thighs, these extracts induced ectopic cartilage and bone. Seven days following continuous in vitro exposure to the same extracts...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer-Verlag
1984
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