A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.

The microsomal triglyceride transfer protein (MTP) has a key function in intracellular apolipoprotein (apo) B lipidation and secretion of very low density lipoprotein (VLDL). A recently discovered functional polymorphism in the promoter of the MTP gene (-493G/T) affects the plasma concentration of l...

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Bibliografische gegevens
Hoofdauteurs: Björn Lundahl, Leren, T, Ose, L, Hamsten, A, Karpe, F
Formaat: Journal article
Taal:English
Gepubliceerd in: 2000