Reconstitution of the core of the malaria parasite glideosome with recombinant Plasmodium class XIV myosin A and Plasmodium actin

Motility of the apicomplexan malaria parasite Plasmodium falciparum is enabled by a multiprotein glideosome complex, whose core is the class XIV myosin motor, PfMyoA, and a divergent Plasmodium actin (PfAct1). Parasite motility is necessary for host-cell invasion and virulence, but studying its mole...

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Bibliographic Details
Main Authors: Bookwalter, CS, Tay, CL, McCrorie, R, Previs, MJ, Lu, H, Krementsova, EB, Fagnant, PM, Baum, J, Trybus, KM
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2017