Bisphosphonate affinity to hydroxyapatite and farnesyl pyrophosphate inhibitory potency, together, drive in vivo efficacy

פריטים דומים

• Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
  מאת: Xia, Z, et al.
  יצא לאור: (2007)
• The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
  מאת: Ebetino, F, et al.
  יצא לאור: (2007)
• Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
  מאת: Xia, Z, et al.
  יצא לאור: (2006)
• A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
  מאת: Ebetino, F, et al.
  יצא לאור: (2008)
• Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
  מאת: Dunford, J, et al.
  יצא לאור: (2006)