Bisphosphonate affinity to hydroxyapatite and farnesyl pyrophosphate inhibitory potency, together, drive in vivo efficacy

Παρόμοια τεκμήρια

• Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
  ανά: Xia, Z, κ.ά.
  Έκδοση: (2007)
• The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
  ανά: Ebetino, F, κ.ά.
  Έκδοση: (2007)
• Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
  ανά: Xia, Z, κ.ά.
  Έκδοση: (2006)
• A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
  ανά: Ebetino, F, κ.ά.
  Έκδοση: (2008)
• Differences between bisphosphonates in binding affinities for hydroxyapatite.
  ανά: Lawson, M, κ.ά.
  Έκδοση: (2010)