Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while ~45% did not (NoTD). Intestinal macrophages are o...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Toapanta, FR, Hu, J, Shirey, KA, Bernal, PJ, Levine, MM, Darton, TC, Waddington, CS, Pollard, AJ, Sztein, MB
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Frontiers Media 2024