The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock

Resistance to the intestinal parasitic helminth Trichuris muris requires T-helper 2 (TH2) cellular and associated IgG1 responses, with expulsion typically taking up to 4 weeks in mice. Here, we show that the time-of-day of the initial infection affects efficiency of worm expulsion, with strong TH2 b...

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Bibliographic Details
Main Authors: Hopwood, TW, Hall, S, Begley, N, Forman, R, Brown, S, Vonslow, R, Saer, B, Little, MC, Murphy, EA, Hurst, RJ, Ray, DW, Macdonald, AS, Brass, A, Bechtold, DA, Gibbs, JE, Loudon, AS, Else, KJ
Format: Journal article
Language:English
Published: Springer Nature 2018