Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

Only one broadly neutralizing anti-HIV antibody, 2G12, recognises the envelope sugars of HIV. In the present study, we show that 2G12 also recognises Candida albicans and Candida tropicalis with high affinity (11 nmol/l) through a carbohydrate-dependent interaction (50% inhibitory concentration for...

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Bibliographic Details
Main Authors: Dunlop, D, Ulrich, A, Appelmelk, B, Burton, D, Dwek, R, Zitzmann, N, Scanlan, C
Format: Journal article
Language:English
Published: Lippincott Williams and Wilkins 2008