The cryo-EM structure of the SNX-BAR Mvp1 tetramer

Sorting nexins (SNX) are a family of PX domain-containing proteins with pivotal roles in trafficking and signaling. SNX-BARs, which also have a curvature-generating Bin/Amphiphysin/Rvs (BAR) domain, have membrane-remodeling functions, particularly at the endosome. The minimal PX-BAR module is a dime...

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Détails bibliographiques
Auteurs principaux: Sun, D, Varlakhanova, NV, Tornabene, BA, Ramachandran, R, Zhang, P, Ford, MGJ
Format: Journal article
Langue:English
Publié: Nature Research 2020