The cryo-EM structure of the SNX-BAR Mvp1 tetramer
Sorting nexins (SNX) are a family of PX domain-containing proteins with pivotal roles in trafficking and signaling. SNX-BARs, which also have a curvature-generating Bin/Amphiphysin/Rvs (BAR) domain, have membrane-remodeling functions, particularly at the endosome. The minimal PX-BAR module is a dime...
Hlavní autoři: | Sun, D, Varlakhanova, NV, Tornabene, BA, Ramachandran, R, Zhang, P, Ford, MGJ |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Nature Research
2020
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