Supertertiary structure analysis and comparison of BET proteins upon bivalent binding
BET proteins (BRD2/3/4/T) contain two bromodomains (BD1 and BD2) and an extra terminal (ET) domain. They act as nuclear scaffolds by recognising acetylated histones and recruiting transcriptional complexes. Although all BETs share high levels of sequence conservation, each has different biological f...
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| Format: | Thesis |
| Language: | English |
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2020
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