Proteasome inhibitors as anti-cancer agents.

The ubiquitin (Ub)-proteasome pathway is the major nonlysosomal pathway of proteolysis in human cells and accounts for the degradation of most short-lived, misfolded or damaged proteins. This pathway is important in the regulation of a number of key biological regulatory mechanisms. Proteins are usu...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Murray, R, Norbury, C
التنسيق: Journal article
اللغة:English
منشور في: 2000