Proteasome inhibitors as anti-cancer agents.

The ubiquitin (Ub)-proteasome pathway is the major nonlysosomal pathway of proteolysis in human cells and accounts for the degradation of most short-lived, misfolded or damaged proteins. This pathway is important in the regulation of a number of key biological regulatory mechanisms. Proteins are usu...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Murray, R, Norbury, C
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2000