Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
Although originally discovered as inhibitors of pencillin-binding proteins, beta-lactams have more recently found utility as serine protease inhibitors. Indeed through their ability to react irreversibly with nucleophilic serine residues they have proved extraordinarily successful as enzyme inhibito...
প্রধান লেখক: | , , , , , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1999
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