Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.

Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.

Although originally discovered as inhibitors of pencillin-binding proteins, beta-lactams have more recently found utility as serine protease inhibitors. Indeed through their ability to react irreversibly with nucleophilic serine residues they have proved extraordinarily successful as enzyme inhibito...

書目詳細資料
Main Authors:	Wilmouth, R, Kassamally, S, Westwood, N, Sheppard, R, Claridge, T, Aplin, RT, Wright, P, Pritchard, G, Schofield, C
格式:	Journal article
語言:	English
出版:	1999

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