The impact of thiopurine S-methyltransferase polymorphisms on azathioprine dose 1 year after renal transplantation.

Azathioprine metabolism is influenced by activity of the enzyme thiopurine S-methyltransferase (TPMT), which varies markedly between individuals. In this study we examined the influence of TPMT gene polymorphisms on azathioprine dose 1 year after renal transplantation. TPMT coding and promoter genot...

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Bibliographic Details
Main Authors: Fabre, M, Jones, D, Bunce, M, Morris, P, Friend, P, Welsh, K, Marshall, SE
Format: Journal article
Language:English
Published: 2004