Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade

Rhodium-catalyzed hydroacylation using alkynes substituted with pendant nucleophiles, delivers linear α,β-unsaturated enone intermediates with excellent regioselectivity. These adducts are used to construct a broad range of diversely substituted, saturated O-, N- and S-heterocycles in a one-pot proc...

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Bibliographic Details
Main Authors: Iwumene, N, Moseley, D, Pullin, R, Willis, M
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2022