Retinal repair by transplantation of photoreceptor precursors.

Retinal repair by transplantation of photoreceptor precursors.

Photoreceptor loss causes irreversible blindness in many retinal diseases. Repair of such damage by cell transplantation is one of the most feasible types of central nervous system repair; photoreceptor degeneration initially leaves the inner retinal circuitry intact and new photoreceptors need only...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Maclaren, R, Pearson, R, MacNeil, A, Douglas, R, Salt, T, Akimoto, M, Swaroop, A, Sowden, J, Ali, R
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2006

Những quyển sách tương tự

Immature neural retinal cells integrate and differentiate into photoreceptors when transplanted into the mouse subreitnal space at post-natal day 1
Bằng: Maclaren, R, et al.
Được phát hành: (2005)

Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.
Bằng: West, E, et al.
Được phát hành: (2008)

Cell transplantation strategies for retinal repair.
Bằng: West, E, et al.
Được phát hành: (2009)

Overexpression of developmentally regulated neurotrophins in the adult mouse retina to facilitate integration of transplanted photoreceptor precursor cells
Bằng: West, E, et al.
Được phát hành: (2008)

Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival.
Bằng: West, E, et al.
Được phát hành: (2012)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
Bằng: Singh, M, et al.
Được phát hành: (2016)

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
Bằng: R. A. Pearson, et al.
Được phát hành: (2016-10-01)

Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
Bằng: Pearson, R, et al.
Được phát hành: (2010)

Manipulation of the Recipient Retinal Environment by Ectopic Expression of Neurotrophic Growth Factors Can Improve Transplanted Photoreceptor Integration and Survival
Bằng: E. L. West, et al.
Được phát hành: (2012-05-01)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
Bằng: Mandeep S. Singh, et al.
Được phát hành: (2016-11-01)

Cone fusion confusion in photoreceptor transplantation
Bằng: MacLaren, R
Được phát hành: (2017)

Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina
Bằng: R. A. Pearson, et al.
Được phát hành: (2010-04-01)

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.
Bằng: West, E, et al.
Được phát hành: (2010)

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.
Bằng: Singh, MS, et al.
Được phát hành: (2013)

Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye.
Bằng: MacNeil, A, et al.
Được phát hành: (2007)

Outer segment formation of transplanted photoreceptor precursor cells.
Bằng: Dominic Eberle, et al.
Được phát hành: (2012-01-01)

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.
Bằng: Budd A Tucker, et al.
Được phát hành: (2011-04-01)

Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice.
Bằng: Budd A Tucker, et al.
Được phát hành: (2015-01-01)

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
Bằng: Anai Gonzalez-Cordero, et al.
Được phát hành: (2017-09-01)

CRX haploinsufficiency compromises photoreceptor precursor translocation and differentiation in human retinal organoids
Bằng: Deng Pan, et al.
Được phát hành: (2023-12-01)

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa
Bằng: Orlans, HO, et al.
Được phát hành: (2019)

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells
Bằng: Saeed Khalili, et al.
Được phát hành: (2018-12-01)

Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina.
Bằng: Kokkinopoulos, I, et al.
Được phát hành: (2008)

Induced pluripotent stem cells and derivative photoreceptor precursors as therapeutic cells for retinal degenerations
Bằng: Rupendra Shrestha, et al.
Được phát hành: (2020-01-01)

Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.
Bằng: Aslam, SA, et al.
Được phát hành: (2013)

Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia.
Bằng: Tolmachova, T, et al.
Được phát hành: (2010)

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa
Bằng: Budd A Tucker, et al.
Được phát hành: (2013-08-01)

Metabolic rescue of cone photoreceptors in retinitis pigmentosa
Bằng: Henry J Kaplan, et al.
Được phát hành: (2021-01-01)

Retinal Thickening and Photoreceptor Loss in HIV Eyes without Retinitis.
Bằng: Cheryl A Arcinue, et al.
Được phát hành: (2015-01-01)

cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates
Bằng: Swathi Lingam, et al.
Được phát hành: (2021-08-01)

AAV-Mediated Expression of Secreted Human Ciliary Neurotropic Factor (hCNTF) Leads to Long-Term Preservation of Cone Photoreceptors in an Autosomal Recessive Model of Retinitis Pigmentosa
Bằng: Lipinski, D, et al.
Được phát hành: (2013)

Inner retinal thickening affects microperimetry thresholds in the presence of photoreceptor thinning in patients with RPGR retinitis pigmentosa
Bằng: Jolly, JK, et al.
Được phát hành: (2020)

Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal
Bằng: Ryan A. Kelley, et al.
Được phát hành: (2020-06-01)

In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.
Bằng: Buch, P, et al.
Được phát hành: (2006)

Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.
Bằng: Sunil K Parapuram, et al.
Được phát hành: (2010-11-01)

Photoreceptor Differentiation following Transplantation of Allogeneic Retinal Progenitor Cells to the Dystrophic Rhodopsin Pro347Leu Transgenic Pig
Bằng: H. Klassen, et al.
Được phát hành: (2012-01-01)

Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
Bằng: Holly Y Chen, et al.
Được phát hành: (2023-03-01)

Neuroprotection of cone photoreceptors in retinitis pigmentosa
Bằng: Lipinski, D, et al.
Được phát hành: (2013)

Multiphoton response of retinal rod photoreceptors
Bằng: Vasilios Alexiades, et al.
Được phát hành: (2007-02-01)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
Bằng: Sang Joon Lee, et al.
Được phát hành: (2025-01-01)