Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse

The essential roles played by Nodal and Bmp signalling during early mouse development have been extensively documented. Here we use conditional deletion strategies to investigate functional contributions made by Nodal, Bmp and Smad downstream effectors during primordial germ cell (PGC) development....

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Bibliographic Details
Main Authors: Senft, AD, Bikoff, EK, Robertson, EJ, Costello, I
Format: Journal article
Language:English
Published: Nature Research 2019