Ruthenium half-sandwich complexes bound to protein kinase Pim-1.

(Figure Presented) Keeping in shape with half a sandwich: The structure of a picomolar organoruthenium inhibitor bound to the ATP-binding site of the protein kinase Pim-1 (see picture) demonstrates that the ruthenium center has solely a structural role in organizing the organic ligands in the three-...

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Main Authors: Debreczeni, J, Bullock, A, Atilla, G, Williams, D, Bregman, H, Knapp, S, Meggers, E
格式: Journal article
语言:English
出版: 2006