Development and clinical application of an innovative fluorescence in situ hybridization technique which detects submicroscopic rearrangements involving telomeres.

We report an innovative fluorescence in situ hybridization technique which exploits a unique resource of 41 telomere-specific probes and allows the simultaneous analysis of the subtelomeric region of every chromosome for deletion, triplication and balanced translocation events. This technique requir...

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Bibliographic Details
Main Authors: Knight, S, Horsley, S, Regan, R, Lawrie, N, Maher, E, Cardy, D, Flint, J, Kearney, L
Format: Journal article
Language:English
Published: 1997