Tenascin-C promotes tumor cell migration and metastasis through integrin α9β1–mediated YAP inhibition
Tenascin-C is an extracellular matrix molecule that drives progression of many types of human cancer, but the basis for its actions remains obscure. In this study, we describe a cell-autonomous signaling mechanism explaining how tenascin-C promotes cancer cell migration in the tumor microenvironment...
Main Authors: | Sun, Z, Schwenzer, A, Rupp, T, Murdamoothoo, M, Vegliante, R, Lefebvre, O, Klein, A, Hussenet, T, Orend, G |
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Format: | Journal article |
Published: |
American Association for Cancer Research
2017
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