Tenascin-C promotes tumor cell migration and metastasis through integrin α9β1–mediated YAP inhibition
Tenascin-C is an extracellular matrix molecule that drives progression of many types of human cancer, but the basis for its actions remains obscure. In this study, we describe a cell-autonomous signaling mechanism explaining how tenascin-C promotes cancer cell migration in the tumor microenvironment...
Hlavní autoři: | , , , , , , , , |
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Médium: | Journal article |
Vydáno: |
American Association for Cancer Research
2017
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