Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.

HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs) are part of the combination therapy currently used to treat HIV infection. The features of a new NNRTI drug for HIV treatment must include selective potent activity against both wild-type virus as well as against mutant virus that have be...

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Bibliographic Details
Main Authors: Freeman, G, Andrews, C, Hopkins, A, Lowell, G, Schaller, LT, Cowan, JR, Gonzales, S, Koszalka, G, Hazen, R, Boone, L, Ferris, R, Creech, K, Roberts, G, Short, SA, Weaver, K, Reynolds, D, Milton, J, Ren, J, Stuart, D, Stammers, D, Chan, J
Format: Journal article
Language:English
Published: 2004