Abnormal whole‑body energy metabolism in iron‑deficient humans despite preserved skeletal muscle oxidative phosphorylation

Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are incompletely characterised, but animal and human experiments suggest the involvement of signalling pathways co-dependent upon oxygen and iron availability, including the pathway associated with hypoxia-inducible factor...

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Bibliographic Details
Main Authors: Frise, M, Holdsworth, D, Johnson, A, Chung, YJ, Curtis, M, Cox, P, Clarke, K, Tyler, D, Roberts, D, Ratcliffe, P, Dorrington, K, Robbins, P
Format: Journal article
Language:English
Published: Springer Nature 2022